As an example, regarding different histologies included in the same group, Schmidt et al. reported a non-significant difference in terms of OS in 321 NSCLC (stage I to III) stratified by PD-L1 status (p = 0.265), whereas survival in SqC demonstrated to be significantly improved (p = 0.04) [28]. Here, CD274 is linked to non-small cell lung carcinoma.