Although CD38 is highly and uniformly expressed on MM cells, and at relatively low levels on normal hematopoietic cells including myeloid and lymphoid cells, as well as in some cells of non-hematopoietic origin [42,43], CD38 expression on normal hematopoietic cells plasma cells, thymocytes, lymphocytes, activated T cells and B cells, dendritic cells, NK cells, erythrocytes, and platelets, is a concern. The gene discussed is CD38; the disease is Miyoshi myopathy.