As a prognostic biomarker, IGF2BP3 expression has been associated with disease progression and decreased survival in a growing list of cancer types, including non-small cell lung cancer [20], colorectal cancer [21], pancreatic ductal adenocarcinoma (PDAC) [22], clear cell renal cell carcinoma (RCC) [23,24], bladder carcinoma [25], breast cancer [26], and leukemia [16], among others [10,27,28,29,30]. The gene discussed is IGF2BP3; the disease is cancer.