This study explores a potential link between HER2 and EBV oncoproteins in gastric cancer, where EBV triggers EMT via PI3K/Akt and Shc-MAPK/Erk1/Erk2 pathways, while HER2 activates EMT-related pathways through phosphorylation, contributing to cancer advancement. Here, ERBB2 is linked to gastric cancer.