Given the highest APN/CD13 and integrin ανβ3 expression levels observed in MCF-7 and MDA-MB-231 tumors, respectively, the most elevated [68Ga]Ga-NGR-RGD accumulation was observed in these tumor types, indicating the target selectivity of the probe (MCF-7: 1.03 ± 0.08%ID/g and MDA-MB-231: 1.04 ± 0.06%ID/g). This evidence concerns the gene ANPEP and neoplasm.