Fifteen-week-old male Swiss nu/nu mice bearing human colorectal adenocarcinoma (LS174T) were intravenously administered with either the CD13 targeting the NGR-pQD ligand or the pQDs without the NGR motif to test the feasibility of the complex in the assessment of tumor-related angiogenesis applying quantitative molecular MRI. The gene discussed is RTN4R; the disease is neoplasm.