Only tumor size, Ki-67, and p53 expression were included in the multivariable analysis, and all these variables were significantly associated with the ODX risk group (tumor size, OR: 3.421, 95% CI: 1.192–9.821, p = 0.022; Ki-67, OR: 1.061, 95% CI: 1.025–1.099, p = 0.001; p53, OR: 7.330, 95% CI: 2.201–24.411, p = 0.001). This evidence concerns the gene MKI67 and neoplasm.