In contrast, old age (≥60 years) (HR 1.20; 95% CI, 1.09–1.32; p < 0.001), a high CEA level (>5 ng/mL) (HR 2.14; 95% CI, 1.89–2.42; p < 0.001), primary right-sided colon cancer (HR 1.35; 95% CI, 1.22–1.51; p < 0.001), metachronous liver metastases (HR 1.26; 95% CI, 1.14–1.39; p < 0.001), and extrahepatic metastasis (HR 1.46; 95% CI, 1.33–1.60; p < 0.001) portend a worse OS (Table 2). Here, CEACAM5 is linked to metastasis.