In a study of the expression of CD45 in typical CLL, aCLL, CLL/PLL, HCL, B-PLL, and B cell-non-Hodgkin lymphoma (B-NHL), Maljaei et al. found lower CD45 density in typical CLL than in the other conditions, including aCLL [71]. This evidence concerns the gene PTPRC and B-cell non-Hodgkin lymphoma.