MAPT and Atrophy: Old cats may develop a syndrome known as Feline Cognitive Dysfunction (FCD) or feline dementia, in which behavioral and cognitive alterations emerge with age-related tau and Aβ deposition, and neurodegenerative changes (e.g., cerebral atrophy, neuronal loss, ventricular enlargement, vascular changes, etc.)[23,25,29,30,31].