Like MAT2A and the methionine transporter SLC43A2, METTL7B is upregulated in several types of cancer (https://www.proteinatlas.org/ENSG00000170439-METTL7B/pathology, accessed on 17 July 2023), thus providing a molecular rationale for elevated methionine-derived enzymatic methanethiol production in cancer cells. This evidence concerns the gene MAT2A and cancer.