Inhibiting glial cell activation during the acute phase of stroke produced long-lasting effects, dramatically reducing (F(3,12) = 29.20, p < 0.0001) neurogenesis at chronic time points (30 d) post-ischemia (BrdU+/NeuN+) in the injured striatum of Ibudilast-treated, MCAO-injured juvenile mice (Figure 3C,F, 9.9 ± 2.5%), compared to vehicle-treated MCAO-injured juveniles (Figure 3B,F, 33.8 ± 2.9%, p < 0.0001). The gene discussed is RBFOX3; the disease is stroke disorder.