Another study demonstrated that CXC motif chemokine ligand 13 (CXCL13), a CXC chemokine specifically binding to CXC chemokine receptor type 5 (CXCR5) to prolong the activation of oncogenic kinases and signaling, is linked to CD163+ M2 TAMs and could also promote the tumor polarization of M2c via IL-10 induction [8]. Here, IL10 is linked to neoplasm.