LGALS9 and glioblastoma: Gal-9, known as an eosinophil chemoattractant and negative modulator of the adaptive immune response, is inhibited by α-lactose, positively related to M2 TAMs, and binds with T cell immunoglobulin and mucin domain 3 (Tim3) to inhibit the immune microenvironment in GBM [43,50,51].