ADA2 and glioblastoma: Zhu et al. showed that Cat Eye Syndrome Critical Region Protein 1 (CECR1), a member of the adenyl-deaminase growth factor family, which is highly expressed in M2 TAMs in GBM, regulates the expression of PDGFB, promotes angiogenesis and pericyte migration, and enhances the expression and deposition of periostin via PDGFB-PDGFRβ signaling.