PLCG2 and autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation: Interestingly, the dysregulation of phospholipase C γ 2 (PLCG2) is known to result in autoinflammatory diseases like Phospholipase Cγ-Associated Antibody Deficiency and Immune Dysregulation (PLAID) [51] and autoinflammation and PLAID (APLAID) [52].