ANXA2 and eosinophilia-myalgia syndrome: In addition, many proteins were also detected in the PF EVs from EMs patients, including peroxiredoxin-1 (PRDX1), histone H2A type 2-C, annexin A2 (ANXA2), inter-a-trypsin inhibitor heavy chain H4 (ITIH4) (fragment), and tubulin a-chain [35].