HP and hepatocellular carcinoma: Fucosylated as well as sialylated glycan structures of serum Hp have been shown to be significantly elevated in patients with HCC when compared to cirrhotics without tumors [188,189], Zhu et al. demonstrated a significant elevation of five N-glycopeptides at sites N184 and N241 during the progression of MASH to HCC (p < 0.05), with an AUC of 0.733 and 0.775, respectively.