In the previous work, we demonstrated that in longer-term diabetes, capsaicin-insensitive low-pH-sensitive types of DRG neurons, caps-, show diabetes-induced upregulation of the Cav3.2 subtype of T-channels in their somas that results in ADP and the appearance of somatic double-spike bursts evoked by threshold current injections [8]. Here, CACNA1H is linked to diabetes mellitus.