GPT and Insulin resistance: Although further studies are warranted, this initial study showed that there was a positive correlation between plasma zonulin levels and body mass index, creatinine, fasting plasma glucose, baseline, first hour, and two-hour glucose levels and the OGTT, haemoglobin A1C (HbA1C), homeostatic model assessment for insulin resistance (HOMA-IR), and alanine aminotransferase (ALT) levels.