TNF and Neoplasm of the liver: A dose of NDEA of 200 mg/kg has been reported to induce liver tumors [14] and could incite chronic inflammation, elevating levels of interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α), and thereby attracting immune cells to the liver tissue [15].