In this sense, we have observed that the expression of the Iba1 microglia marker was increased in the retinas of the rd1 mice (an animal model of RP) compared to the control group at PN17 (after the period of maximum death of the rods), PN28 (at the beginning of the period of death of the cones), and PN42. The gene discussed is PDE6B; the disease is retinitis pigmentosa 1.