PINK1 and idiopathic pulmonary fibrosis: In another paper, the authors saw that the knocking out of PINK1 in mice would lead to an increase of mitochondrial DNA (mtDNA) oxidation in lung tissue, a finding that was also observed in human cells from IPF lung samples, where not only PINK1 expression is lower when compared to control samples, but also associated to an increase of mtDNA oxidation [68].