MYCN and neuroblastoma: The analysis of RNA-seq data from 30 high-risk neuroblastoma tumors bearing MYCN amplification shows the over-expression of essential genes such as the HAND2, PHOX2B, and GATA3 transcription factors, the proline synthesis regulators ALDH18A1 and PYCR1, and the synaptic vesicle dopamine transporter VMAT2 [10].