NLRP3 and acute kidney injury: Furthermore, since ferroptosis is associated with ferric ion transport and fatty acid metabolism and has been proven involved in the development of S-AKI [20,21], we then extracted 484 ferroptosis-related genes (ferroptosis) from the FerrDb V2 database and intersected them with genes upregulated in WT mice after LPS administration (WT + LPS up) and genes downregulated in Nlrp3−/− mice treated with LPS (Nlrp3−/− + LPS down).