In the present study, all the liver function tests (ALP, ALT, and AST), GGT, LDH, lipid markers (HDL, HDL, cholesterol, TAGs), macromolecular oxidation products (MDA, NO), and inflammatory markers (IL-6, TNF-α, and CRP) were prominently elevated in the HCC rat group as compared to the normal, while the cellular redox markers (CAT, GSH) were highly compromised in the same. Here, CRP is linked to hepatocellular carcinoma.