CRTC1 and fragile X-associated tremor/ataxia syndrome: In the later study, correlations between measures of mitochondrial and nonmitochondrial respiratory activity, AMPK, and TORC1 cellular protein kinases, and the scores representing motor, cognitive, and neuropsychiatric impairments, were found with the CGG repeat size, and a hyperactivity of cellular bioenergetic components was significantly associated with motor-impairment measures, including tremor–ataxia, parkinsonism, and neuropsychiatric changes, predominantly in the FXTAS subgroup [182].