IL18 and eye inflammation: Accordingly, significantly decreased concentrations of IL-1β, IL-18, TNF-α, IL-6, IL-1α, and IFN-γ and an increased concentration of IL-10 were observed in the eyes of BAC-treated mice that received MSC-Exos, suggesting that MSCs prevented the progression of BAC-induced corneal injury and inhibited progression of DED by suppressing NLRP3-driven eye inflammation [29].