Moreover, the difference in the myogenic response between the MA segments isolated from the WT and LPP-KO mice was maintained when these were derived from 6-month-old (6 M) animals made hypertensive for 21 days using the deoxycorticosterone acetate (DOCA)-salt model of hypertension (Figure 9f), [23]. The gene discussed is LPP; the disease is hypertensive disorder.