The study suggested that exosomal delivery of lncRNA A2M-AS1 ameliorates H/R-induced cardiomyocyte apoptosis and oxidative stress by sponging miR-556-5p and increasing X-linked inhibitor of apoptosis protein (XIAP), providing insights into the pathogenesis of myocardial ischemia/reperfusion (I/R) injury [88]. This evidence concerns the gene XIAP and myocardial ischemia.