For example, impairment in the interaction of the SH3-containing protein SHANK with a wide spectrum of its target cytoskeletal proteins has an impact on autism/schizophrenia pathophysiology, and NAP, through regulating SH3-mediated protein interactions, exhibits a favorable effect on these cytoskeletal interactions and the subsequent cellular processes [3]. This evidence concerns the gene CTNNBL1 and schizophrenia.