The identified functions of the genes that were deleted and those amplified suggest that their manipulation would offer an advantage to the growing tumours—most notably, the deletion of TS genes (e.g., immunity ITM2A, and metabolism genes; Table S5, Tab#2) and the amplification of oncogenes (e.g., MAGE genes; Table S5, Tab#3). This evidence concerns the gene ITM2A and neoplasm.