The current data suggest that the development of hepatic fibrosis processes is orchestrated by parenchymal and mesenchymal cells, releasing a complex network of pro-fibrogenic cytokines, and predominantly transforming growth factor beta 1 (TGF-β1), which is involved in cells’ activation and differentiation into a heterogeneous population of myofibroblasts [2]. The gene discussed is TGFB1; the disease is Hepatic fibrosis.