Two further GWAS-identified CAD-associated genes exerting their effects through smooth muscle cell behaviours are MFGE8 (Milk Fat Globule-EGF factor 8), an integrin-binding glycoprotein, and MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11). The gene discussed is MFGE8; the disease is coronary artery disorder.