The 36 genes linked to the NAFLD pathway, represented among the specifically up-regulated genes in CAR−/− females (Figure 5C), are in Figure 5E. These genes were traced in the NAFLD Kegg pathway map (hsa04932), representative of a stage-dependent progression of NAFLD, and are mainly involved in β-oxidation (Ndufa-b-s-c, Sdha-b, Cyc1, Uqcrq-c-s, Cox1-5-6-7-8) and inflammation (Jun) which are mechanisms disrupted in NASH conditions. The gene discussed is CYC1; the disease is metabolic dysfunction-associated steatohepatitis.