AKT1 is also implicated in the increased migratory capacity of cancer, so it was unsurprising to see that the overexpression of miR-143-3p significantly reduced migration in RWPE1, DU145 and PC3 cell lines, while the inhibition of miR-143-3p significantly increased migration in RWPE1 cell lines (Figure 4b, Supplementary Figure S5). Here, AKT1 is linked to cancer.