This suggests that YWHAG is often overexpressed in most solid tumors, such as pancreatic, gastric, lung, breast, and hepatocellular carcinoma, and that YWHAG overexpression leads to the activation of signaling pathways that drive cancer progression.[7, 22] High YWHAG expression correlates with poor prognosis in patients. The gene discussed is YWHAG; the disease is hepatocellular carcinoma.