Here we show that an increased production of key cytokines (IL‐6, IL‐8, MCP‐1 and CXCL1), known to facilitate transmigration of breast cancer cells across the BBB (Fares et al., 2021), were increased following NHA exposure to MBM‐EVs or miR‐146a‐5p mimic. This evidence concerns the gene CXCL1 and breast carcinoma.