Notably, in genito-urinary (BLCA, KICH, and KIRP), gastrointestinal (LIHC and PAAD), and brain (LGG) tumors, as well as tumors of other origins (ACC, MESO, SARC, and SKCM), WDHD1 exhibited good prognostic value, although there were scarce reports explaining its specific role in these tumors. This evidence concerns the gene WDHD1 and pancreatic adenocarcinoma.