To gain better and deeper insights into the impact of WDHD1 on the response to immune checkpoint blockade (ICB) treatment, we evaluated the tumor immune dysfunction and exclusion (TIDE) scores of WDHD1 in five specific types of cancer: BLCA, LGG, LIHC, LUAD, and PAAD. Here, WDHD1 is linked to pancreatic adenocarcinoma.