There were no significant differences in terms of patient age, sex, Charlson Comorbidity score (CCI), Peptic Ulcer Perforation (PULP) score, Mannheim Peritonitis Index (MPI), preoperative white blood count (WBC), hemoglobin, C reactive protein (CRP) level, or body mass index (BMI) between the two groups. This evidence concerns the gene CRP and peptic ulcer disease.