BRD4 and glioblastoma: To understand the epigenomic landscape of glioblastoma and related glial progenitor cells, we performed chromatin immunoprecipitation followed by sequencing (ChIP-seq) of H4K5acK8ac, H3K27ac, H3K4me3, H3K4me1, and BRD4, in three human glial cell lines: a patient-derived GSC line (0316-GSC) [39], a glioblastoma line (U87), and microglia cell line (C13NJ) [40].