FOXP3 and type 1 diabetes mellitus: The elevated expression of FOXP3 we observed in Tregs from T1D cases, as compared to controls, could contribute to the altered expression of downstream targets including these nine splicing factor genes, resulting in the elevated inclusion of poison cassette exons observed in some of these genes, such as SRSF7, without appearing to significantly alter the expression of protein-coding isoforms of these genes.