TGFB1 and liver dysplastic nodule: In addition, as demonstrated by GSEA, the curated kidney-aging-related gene set “RODWELL_AGING_KIDNEY_UP” exhibited significant enrichment in high expression of TGFβ1 as compared with low expression of TGFβ1 in renal tubulointerstitial specimens procured from patients with DN or healthy living donors based on the ERCB study (Fig. 1B).