The expression differences of CCNB1 between tumor and adjacent normal tissues for the different tumors of the TCGA database are shown in Fig. 1A. For certain tumors without corresponding normal tissues in TCGA, the expression differences in the GTEx (Genotype-tissue expression) database were analyzed, and box plots were obtained via the GEPIA2 website (Fig. 1B). Here, CCNB1 is linked to neoplasm.