The DFS analysis data showed that high CCNB1 expression indicated poor prognosis among all cancer types (ACC (P = 0.011), HNSC (P = 0.042), KIRC (P = 0.0029), KIRP (P < 0.001), LGG (P = 0.0051), LIHC (P < 0.001), LUAD (P = 0.0079), MESO (P = 0.034), PAAD (P = 0.0091), PRAD (P = 0.0032), SARC (P = 0.05), and UVM (P = 0.0013)). The gene discussed is CCNB1; the disease is cancer.