For lateral-genes, these showed enrichment for epilepsy-related (generalised and myoclonic), bipolar disorder, schizophrenia and other generalised movement/neurological conditions (Supplementary Data 11), with genes for sodium/potassium transport and channels (ATP1A3/KCNA1/KCNA2/KCNC1/SCN1B/SCN8A), and glutamate receptors (GRM1/GRM4) implicated across disorders. The gene discussed is SCN8A; the disease is bipolar disorder.