TLX2 and neoplasm: In this study, we performed TLX2 analysis in pan cancer to investigate the association between TLX2 expression and prognosis, TLX2 expression and staging, the relationship between microsatellite instability (MSI) and tumor mutational load (TMB), genetic variation analysis of TLX2, the relationship between TLX2 expression and immune infiltration, the relationship between TLX2 expression and immune checkpoint genes (ICG), possible regulatory networks of TLX2, TLX2-mediated drug sensitization, TLX2 expression pattern in single cells and its relationship with functional status of the cancer.