As shown in Fig. 9, TLX2 was positively or negatively correlated with the expression of immune checkpoint genes in 6 tumor types (BLCA, BRCA, GBM, HNSC, STAD, and THYM); TLX2 expression was negatively correlated with the expression of immune checkpoint genes in 9 tumor types (CESC, ESCA, KIRP, LGG, LUAD, LUSC, PCPG, THCA, and UCEC); TLX2 expression was positively correlated with the expression of immune checkpoint genes in 12 tumors, including (COAD, DLBC, KICH, KIRC, LAML, LIHC, OC, PAAD, READ, SKCM, TGCT, and UVM). This evidence concerns the gene TLX2 and neoplasm.