WEE1 and neoplasm: Taking cues from our and others’ previous studies [24, 25], we reasoned that, by inhibiting the cell cycle checkpoint kinase Wee1, UNC0379-DNA damaged, cell cycle arrested cells should bypass safeguard checkpoints, progressing to mitosis, where they are expected to die by a caspase-mediated, tumor suppressor mechanism known as mitotic catastrophe [26–29].