ALOX5 and polyp of large intestine: Consistent with biological relevance of the ALOX5 and ALOX12 SNPs found to be associated with differential colorectal polyp risk in aspirin users in the seAFOod trial, these SNPs were all associated with expression quantitative trait loci for ALOX5 and ALOX12 in the sigmoid and transverse colon in the Genotype-Tissue Expression Project (GTEx) database.