The Mon Fn1 cell population is characterized by inflammatory features, including increased expression of the chemokine receptors Ccr2 and Ccr1 facilitating cell recruitment, immune suppression and tumor-promoting factors such as galectins (Lgals3/9), and the NLRP3 inflammasome inhibitor Tmem176b (Fig. 3G). Here, FN1 is linked to neoplasm.