The associated region on this chromosome was large (7–8Mb in size) and included 12 genes listed in cancer pathways: SP1, ESPL1, ITGB7, EIF4B, ATF1, WNT1, WNT10B, ADCY6, CCNT1, PFKM, COL2A1, and HDAC7. This evidence concerns the gene COL2A1 and cancer.