APOA1 and psoriasis: However, no causal effect of psoriasis on HDL cholesterol (OR: 0.997, 95% CI: 0.989–1.006, p = 0.534) and apolipoprotein A1 abnormalities (OR: 0.994, 95% CI: 0.986–1.002, p = 0.142) was determined using the random-effect IVW method (Figure 2A, Supplementary Table S12).