TYMP and colorectal carcinoma: Interestingly, a recent study by Jia et al. (2023) showed that the S471L variant in the TP gene might be used as a prognostic marker to predict the overall survival (OS) rate and disease-free survival (DFS) rate for CRC patients treated with capecitabine-based adjuvant chemotherapy through mediation of the mRNA expression of the TP gene [25].