All diffuse adult-type astrocytomas, IDH-mutants, are considered a single type and are graded as 2, 3, or 4; oligodendroglioma, IDH-mutant, and 1p/19q-codeleted are graded as 2, 3; and glioblastomas comprise only IDH-wildtype tumors and are graded as 4. Here, IDH1 is linked to glioblastoma.